RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

Receptor for Advanced Glycation Endproducts (RAGE), a multiligand receptor in the immunoglobulin superfamily, functions as a signal-transducing cell surface acceptor for amyloid-beta peptide (Aβ). In view of increased neuronal expression of RAGE in Alzheimer's disease, a murine model was develo...

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Detalhes bibliográficos
Main Authors: Arancio, Ottavio, Zhang, Hui Ping, Chen, Xi, Lin, Chang, Trinchese, Fabrizio, Puzzo, Daniela, Liu, Shumin, Hegde, Ashok, Yan, Shi Fang, Stern, Alan, Luddy, John S, Lue, Lih-Fen, Walker, Douglas G, Roher, Alex, Buttini, Manuel, Mucke, Lennart, Li, Weiying, Schmidt, Ann Marie, Kindy, Mark, Hyslop, Paul A, Stern, David M, Du Yan, Shirley Shi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524347/
https://ncbi.nlm.nih.gov/pubmed/15457210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600415
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