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Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport

Sec1/Munc18 (SM) proteins are central to intracellular transport and neurotransmitter release but their exact role is still elusive. Several SM proteins, like the neuronal N-Sec1 and the yeast Sly1 protein, bind their cognate t-SNAREs with high affinity. This has been thought to be critical for thei...

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Detalhes bibliográficos
Main Authors: Peng, Renwang, Gallwitz, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524344/
https://ncbi.nlm.nih.gov/pubmed/15372079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600410
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