An internal ribosome binding site can be used to select for homologous recombinants at an immunoglobulin heavy-chain locus.

The encephalomyocarditis virus (EMCV) leader sequence is responsible for efficient, cap-independent translation initiation from the viral RNA. It has been used to increase the expression of internal coding regions on polycistronic mRNA encoded by recombinant DNA constructs. We have designed a sequen...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wood, C R, Morris, G E, Alderman, E M, Fouser, L, Kaufman, R J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8006
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