CCL22 DIVERTS T REGULATORY CELLS AND CONTROLS THE GROWTH OF MELANOMA

T regulatory cells (Treg) avert autoimmunity but their increased levels in melanoma confer a poor prognosis. To explore the basis for Treg accumulation in melanoma, we evaluated chemokine expression in patients. A 5-fold increase was documented in the Treg chemoattractants CCL22 and CCL1 in melanoma...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Klarquist, Jared, Tobin, Kristen, Oskuei, Peyman Farhangi, Henning, Steven W., Fernandez, Manuel F., Dellacecca, Emilia R., Navarro, Flor C., Eby, Jonathan M., Chatterjee, Shilpak, Mehrotra, Shikhar, Clark, Joseph I., Le Poole, I. Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242486/
https://ncbi.nlm.nih.gov/pubmed/27634754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0618
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