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Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination

NUB1 (Nedd8 ultimate buster 1) is an adaptor protein which negatively regulates the ubiquitin-like protein Nedd8 as well as neddylated proteins levels through proteasomal degradation. However, molecular mechanisms underlying this function are not completely understood. Here, we report that the oncog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bonacci, Thomas, Audebert, Stéphane, Camoin, Luc, Baudelet, Emilie, Iovanna, Juan-Lucio, Soubeyran, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242482/
https://ncbi.nlm.nih.gov/pubmed/28099510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169988
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