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Inflammatory bowel disease reveals the kinase activity of KSR1
Kinase suppressor of Ras-1 (KSR1) is a recently identified member of the EGFR–Ras–Raf-1–MAPK signaling pathway. A new study demonstrates that KSR1 protects intestinal epithelium from TNF-α–induced apoptosis, abrogating inflammatory bowel disease (IBD). Since its discovery, there has been disagreemen...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524240/ https://ncbi.nlm.nih.gov/pubmed/15520853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200423441 |
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