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Capturing a Dynamic Chaperone–Substrate Interaction Using NMR-Informed Molecular Modeling
Chaperones maintain a healthy proteome by preventing aggregation and by aiding in protein folding. Precisely how chaperones influence the conformational properties of their substrates, however, remains unclear. To achieve a detailed description of dynamic chaperone–substrate interactions, we fused s...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5242313/ https://ncbi.nlm.nih.gov/pubmed/27415450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02382 |
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