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Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice

Selenium (Se) is a trace metalloid essential for life, but its nutritional and physiological roles during the aging process remain elusive. While telomere attrition contributes to replicative senescence mainly through persistent DNA damage response, such an aging process is mitigated in mice with in...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Wu, Ryan T., Cao, Lei, Mattson, Elliot, Witwer, Kenneth W., Cao, Jay, Zeng, Huawei, He, Xin, Combs, Gerald F., Cheng, Wen‐Hsing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242309/
https://ncbi.nlm.nih.gov/pubmed/27653523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12529
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