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Distinct inflammatory phenotypes of microglia and monocyte‐derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology

Alzheimer's disease (AD) is a neurodegenerative disease characterized by formation of amyloid‐β (Aβ) plaques, activated microglia, and neuronal cell death leading to progressive dementia. Recent data indicate that microglia and monocyte‐derived macrophages (MDM) are key players in the initiatio...

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Detalhes bibliográficos
Publicado no:Aging Cell
Principais autores: Martin, Elodie, Boucher, Céline, Fontaine, Bertrand, Delarasse, Cécile
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242297/
https://ncbi.nlm.nih.gov/pubmed/27723233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12522
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