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Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity

Caloric restriction (CR) protects against many cerebral pathological conditions that are associated with excitotoxic damage and calcium overload, although the mechanisms are still poorly understood. Here we show that CR strongly protects against excitotoxic insults in vitro and in vivo in a manner a...

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Publicat a:Aging Cell
Autors principals: Amigo, Ignacio, Menezes‐Filho, Sergio Luiz, Luévano‐Martínez, Luis Alberto, Chausse, Bruno, Kowaltowski, Alicia J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242290/
https://ncbi.nlm.nih.gov/pubmed/27619151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12527
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