Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181

BACKGROUND: Chronic myelogenous leukemia (CML) has unsatisfactory treatment efficacy at present. As the major component of red orpiment, tetra-arsenic tetra-sulfide (As(4)S(4)) has been recently used in treating leukemia, but with unclear mechanism targeting CML. MicroRNA (miR) is a group of endogen...

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Bibliografiske detaljer
Udgivet i:Med Sci Monit
Main Authors: Gong, Jiangjiang, Zheng, Shunli, Zhang, Lei, Wang, Yi, Meng, Jiali
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2017
Fag:
Lab/In Vitro Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242199/
https://ncbi.nlm.nih.gov/pubmed/28072759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.899214
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