5’UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia

Thrombocytopenia 2 (THC2) is an inherited disorder caused by monoallelic single nucleotide substitutions in the 5’UTR of the ANKRD26 gene. Patients have thrombocytopenia and increased risk of myeloid malignancies, in particular, acute myeloid leukemia (AML). Given the association of variants in the...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Hematol Oncol
Auteurs principaux: Marconi, Caterina, Canobbio, Ilaria, Bozzi, Valeria, Pippucci, Tommaso, Simonetti, Giorgia, Melazzini, Federica, Angori, Silvia, Martinelli, Giovanni, Saglio, Giuseppe, Torti, Mauro, Pastan, Ira, Seri, Marco, Pecci, Alessandro
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Letter to the Editor
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242010/
https://ncbi.nlm.nih.gov/pubmed/28100250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0382-y
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