Repo-Man/PP1 regulates heterochromatin formation in interphase

Repo-Man is a protein phosphatase 1 (PP1) targeting subunit that regulates mitotic progression and chromatin remodelling. After mitosis, Repo-Man/PP1 remains associated with chromatin but its function in interphase is not known. Here we show that Repo-Man, via Nup153, is enriched on condensed chroma...

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Publicat a:Nat Commun
Autors principals: de Castro, Inês J., Budzak, James, Di Giacinto, Maria L., Ligammari, Lorena, Gokhan, Ezgi, Spanos, Christos, Moralli, Daniela, Richardson, Christine, de las Heras, Jose I., Salatino, Silvia, Schirmer, Eric C., Ullman, Katharine S., Bickmore, Wendy A., Green, Catherine, Rappsilber, Juri, Lamble, Sarah, Goldberg, Martin W., Vinciotti, Veronica, Vagnarelli, Paola
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241828/
https://ncbi.nlm.nih.gov/pubmed/28091603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14048
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