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Glyco-engineering for the production of recombinant IgA1 with distinct mucin-type O-glycans in plants

IgA nephropathy (IgAN) is a common autoimmune disease that is characterized by formation and deposition of IgA1-containing immune complexes frequently leading to end-stage kidney disease. The IgA1 in these immune complexes carries aberrantly glycosylated O-glycans. In circulating IgA1 these galactos...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Dicker, Martina, Maresch, Daniel, Strasser, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241791/
https://ncbi.nlm.nih.gov/pubmed/27333379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1201251
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