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Repression of the interferon signal transduction pathway by the adenovirus E1A oncogene.

The signal transduction pathway initiated by type I interferon (alpha and beta interferons) is inhibited by expression of the adenovirus type 5 E1A oncogene. Cotransfection analyses with the E1A oncogene and an interferon-stimulated reporter gene show that mutations within an amino-terminal domain o...

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Autors principals: Gutch, M J, Reich, N C
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC52415/
https://ncbi.nlm.nih.gov/pubmed/1654549
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