Base changes in tumour DNA have the power to reveal the causes and evolution of cancer

Next-generation sequencing (NGS) technology has demonstrated that the cancer genomes are peppered with mutations. Although most somatic tumour mutations are unlikely to have any role in the cancer process per se, the spectra of DNA sequence changes in tumour mutation catalogues have the potential to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Hollstein, M, Alexandrov, L B, Wild, C P, Ardin, M, Zavadil, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241425/
https://ncbi.nlm.nih.gov/pubmed/27270430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.192
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