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Gene therapy with mesenchymal stem cells expressing IFN‐ß ameliorates neuroinflammation in experimental models of multiple sclerosis

BACKGROUND AND PURPOSE: Recombinant IFN‐ß is one of the first‐line treatments in multiple sclerosis (MS), despite its lack of efficacy in some patients. In this context, mesenchymal stem cells (MSCs) represent a promising therapeutic alternative due to their immunomodulatory properties and multipote...

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發表在:Br J Pharmacol
Main Authors: Marin‐Bañasco, C, Benabdellah, K, Melero‐Jerez, C, Oliver, B, Pinto‐Medel, M J, Hurtado‐Guerrero, I, de Castro, F, Clemente, D, Fernández, O, Martin, F, Leyva, L, Suardíaz, M
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241389/
https://ncbi.nlm.nih.gov/pubmed/27882538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13674
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