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Gene therapy with mesenchymal stem cells expressing IFN‐ß ameliorates neuroinflammation in experimental models of multiple sclerosis
BACKGROUND AND PURPOSE: Recombinant IFN‐ß is one of the first‐line treatments in multiple sclerosis (MS), despite its lack of efficacy in some patients. In this context, mesenchymal stem cells (MSCs) represent a promising therapeutic alternative due to their immunomodulatory properties and multipote...
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發表在: | Br J Pharmacol |
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Main Authors: | , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
John Wiley and Sons Inc.
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241389/ https://ncbi.nlm.nih.gov/pubmed/27882538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13674 |
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