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Glutamate and α-ketoglutarate: key players in glioma metabolism

Glioblastoma multiforme (GBM), or grade IV astrocytoma, is the most common type of primary brain tumor. It has a devastating prognosis with a 2-year-overall survival rate of only 26 % after standard treatment, which includes surgery, radiation, and adjuvant chemotherapy with temozolomide. Also lower...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Amino Acids
Hauptverfasser: Maus, Andreas, Peters, Godefridus J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Vienna 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241329/
https://ncbi.nlm.nih.gov/pubmed/27752843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2342-9
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