Priming increases the anti-tumor effect and therapeutic window of (177)Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1

BACKGROUND: (177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rarely seen, and optimization of treatment protocols is needed. In vitro studies have shown...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Dalmo, Johanna, Spetz, Johan, Montelius, Mikael, Langen, Britta, Arvidsson, Yvonne, Johansson, Henrik, Parris, Toshima Z., Helou, Khalil, Wängberg, Bo, Nilsson, Ola, Ljungberg, Maria, Forssell-Aronsson, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241264/
https://ncbi.nlm.nih.gov/pubmed/28097640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0247-y
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