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Overview of the SAMPL5 host–guest challenge: Are we doing better?

The ability to computationally predict protein-small molecule binding affinities with high accuracy would accelerate drug discovery and reduce its cost by eliminating rounds of trial-and-error synthesis and experimental evaluation of candidate ligands. As academic and industrial groups work toward t...

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Bibliografiske detaljer
Udgivet i:J Comput Aided Mol Des
Main Authors: Yin, Jian, Henriksen, Niel M., Slochower, David R., Shirts, Michael R., Chiu, Michael W., Mobley, David L., Gilson, Michael K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241188/
https://ncbi.nlm.nih.gov/pubmed/27658802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-016-9974-4
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