Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency

Serum levels of choline and its derivatives are lower in patients with inflammatory bowel disease (IBD) than in healthy individuals. However, the effect of choline deficiency on the severity of colitis has not been investigated. In the present study, we investigated the role of choline deficiency in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sagami, Shintaro, Ueno, Yoshitaka, Tanaka, Shinji, Fujita, Akira, Niitsu, Hiroaki, Hayashi, Ryohei, Hyogo, Hideyuki, Hinoi, Takao, Kitadai, Yasuhiko, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241147/
https://ncbi.nlm.nih.gov/pubmed/28095507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169681
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