Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway

Proliferative vitreoretinopathy (PVR) is the main cause of failure following retinal detachment surgery. Transforming growth factor (TGF)-β2-induced epithelial-to-mesenchymal transition (EMT) plays an important role in the development of PVR, and EMT inhibition decreases collagen gel contraction and...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Chen, Ching-Long, Chen, Yi-Hao, Tai, Ming-Cheng, Liang, Chang-Min, Lu, Da-Wen, Chen, Jiann-Torng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241127/
https://ncbi.nlm.nih.gov/pubmed/28138219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S126743
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