The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc

Nuclear receptors were originally defined as endocrine sensors in humans, leading to the identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear receptors have no known ligand, suggesting new ligand classes remain to be discovered. Furthermore, nuclear receptors a...

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Publicat a:PLoS Biol
Autors principals: Warnhoff, Kurt, Roh, Hyun C., Kocsisova, Zuzana, Tan, Chieh-Hsiang, Morrison, Andrew, Croswell, Damari, Schneider, Daniel L., Kornfeld, Kerry
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240932/
https://ncbi.nlm.nih.gov/pubmed/28095401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000094
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