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The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc

Nuclear receptors were originally defined as endocrine sensors in humans, leading to the identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear receptors have no known ligand, suggesting new ligand classes remain to be discovered. Furthermore, nuclear receptors a...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Warnhoff, Kurt, Roh, Hyun C., Kocsisova, Zuzana, Tan, Chieh-Hsiang, Morrison, Andrew, Croswell, Damari, Schneider, Daniel L., Kornfeld, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240932/
https://ncbi.nlm.nih.gov/pubmed/28095401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000094
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