Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies

Large-scale genome-wide association results are typically obtained from a fixed-effects meta-analysis of GWAS summary statistics from multiple studies spanning different regions and/or time periods. This approach averages the estimated effects of genetic variants across studies. In case genetic effe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: de Vlaming, Ronald, Okbay, Aysu, Rietveld, Cornelius A., Johannesson, Magnus, Magnusson, Patrik K. E., Uitterlinden, André G., van Rooij, Frank J. A., Hofman, Albert, Groenen, Patrick J. F., Thurik, A. Roy, Koellinger, Philipp D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240919/
https://ncbi.nlm.nih.gov/pubmed/28095416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006495
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados