Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin

Glioblastoma multiforme (GBM) is an intractable tumor despite therapeutic advances, principally because of its invasive properties. Radiation is a staple in therapeutic regimens, although cells surviving radiation can become more aggressive and invasive. Subtraction hybridization identified melanoma...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kegelman, Timothy P., Wu, Bainan, Das, Swadesh K., Talukdar, Sarmistha, Beckta, Jason M., Hu, Bin, Emdad, Luni, Valerie, Kristoffer, Sarkar, Devanand, Furnari, Frank B., Cavenee, Webster K., Wei, Jun, Purves, Angela, De, Surya K., Pellecchia, Maurizio, Fisher, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240699/
https://ncbi.nlm.nih.gov/pubmed/28011764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616100114
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