Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin

Glioblastoma multiforme (GBM) is an intractable tumor despite therapeutic advances, principally because of its invasive properties. Radiation is a staple in therapeutic regimens, although cells surviving radiation can become more aggressive and invasive. Subtraction hybridization identified melanoma...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kegelman, Timothy P., Wu, Bainan, Das, Swadesh K., Talukdar, Sarmistha, Beckta, Jason M., Hu, Bin, Emdad, Luni, Valerie, Kristoffer, Sarkar, Devanand, Furnari, Frank B., Cavenee, Webster K., Wei, Jun, Purves, Angela, De, Surya K., Pellecchia, Maurizio, Fisher, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240699/
https://ncbi.nlm.nih.gov/pubmed/28011764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616100114
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