Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin

Glioblastoma multiforme (GBM) is an intractable tumor despite therapeutic advances, principally because of its invasive properties. Radiation is a staple in therapeutic regimens, although cells surviving radiation can become more aggressive and invasive. Subtraction hybridization identified melanoma...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kegelman, Timothy P., Wu, Bainan, Das, Swadesh K., Talukdar, Sarmistha, Beckta, Jason M., Hu, Bin, Emdad, Luni, Valerie, Kristoffer, Sarkar, Devanand, Furnari, Frank B., Cavenee, Webster K., Wei, Jun, Purves, Angela, De, Surya K., Pellecchia, Maurizio, Fisher, Paul B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240699/
https://ncbi.nlm.nih.gov/pubmed/28011764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616100114
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