Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration

Retinal ganglion cells (RGCs), the projection neurons of the eye, cannot regenerate their axons once the optic nerve has been injured and soon begin to die. Whereas RGC death and regenerative failure are widely viewed as being cell-autonomous or influenced by various types of glia, we report here th...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Li, Yiqing, Andereggen, Lukas, Yuki, Kenya, Omura, Kumiko, Yin, Yuqin, Gilbert, Hui-Ya, Erdogan, Burcu, Asdourian, Maria S., Shrock, Christine, de Lima, Silmara, Apfel, Ulf-Peter, Zhuo, Yehong, Hershfinkel, Michal, Lippard, Stephen J., Rosenberg, Paul A., Benowitz, Larry
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240690/
https://ncbi.nlm.nih.gov/pubmed/28049831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616811114
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