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Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone

We report here that autocrine production of human growth hormone (hGH) results in a phenotypic conversion of mammary carcinoma cells such that they exhibit the morphological and molecular characteristics of a mesenchymal cell, including expression of fibronectin and vimentin. Autocrine production of...

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Bibliografiske detaljer
Main Authors: Mukhina, Svetlana, Mertani, Hichem C., Guo, Ke, Lee, Kok-Onn, Gluckman, Peter D., Lobie, Peter E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC524067/
https://ncbi.nlm.nih.gov/pubmed/15353581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405881101
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