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Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes

The generation of hepatocytes that are derived from human adipose stem cells (hASCs) represents an alternative to human hepatocytes for individualized therapeutic and pharmaceutical applications. However, the mechanisms facilitating hepatocyte differentiation from hASCs are not well understood. Here...

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Publicat a:Sci Rep
Autors principals: Huang, Jieqiong, Guo, Xinyue, Li, Weihong, Zhang, Haiyan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240561/
https://ncbi.nlm.nih.gov/pubmed/28094799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40716
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