Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

Background: Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid-β (Aβ) peptide between cerebrospinal fluid (CSF) and plasma compartments. Objective: To determine whether plasma exchange (PE) with albumin replacement was able to modify Aβ concentrati...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Boada, Mercè, Anaya, Fernando, Ortiz, Pilar, Olazarán, Javier, Shua-Haim, Joshua R., Obisesan, Thomas O., Hernández, Isabel, Muñoz, Joan, Buendia, Mar, Alegret, Montserrat, Lafuente, Asunción, Tárraga, Lluís, Núñez, Laura, Torres, Mireia, Grifols, Joan Ramon, Ferrer, Isidre, Lopez, Oscar L., Páez, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240541/
https://ncbi.nlm.nih.gov/pubmed/27911295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160565
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