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Potential of gene drives with genome editing to increase genetic gain in livestock breeding programs

BACKGROUND: This paper uses simulation to explore how gene drives can increase genetic gain in livestock breeding programs. Gene drives are naturally occurring phenomena that cause a mutation on one chromosome to copy itself onto its homologous chromosome. METHODS: We simulated nine different breedi...

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Publicado en:Genet Sel Evol
Autores principales: Gonen, Serap, Jenko, Janez, Gorjanc, Gregor, Mileham, Alan J., Whitelaw, C. Bruce A., Hickey, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240390/
https://ncbi.nlm.nih.gov/pubmed/28093068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-016-0280-3
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