SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers

BACKGROUND: DNA methylation regulates together with other epigenetic mechanisms the transcriptional activity of genes and is involved in the pathogenesis of malignant diseases including lung cancer. In non-small cell lung cancer (NSCLC) various tumor suppressor genes are already known to be tumor-sp...

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Publicado en:Mol Cancer
Autores principales: Altenberger, Corinna, Heller, Gerwin, Ziegler, Barbara, Tomasich, Erwin, Marhold, Maximilian, Topakian, Thais, Müllauer, Leonhard, Heffeter, Petra, Lang, György, End-Pfützenreuter, Adelheid, Döme, Balazs, Arns, Britt-Madeleine, Klepetko, Walter, Zielinski, Christoph C., Zöchbauer-Müller, Sabine
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240214/
https://ncbi.nlm.nih.gov/pubmed/28093071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0568-5
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