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Improved genome sequencing using an engineered transposase

BACKGROUND: Next-generation sequencing (NGS) has transformed genomic research by reducing turnaround time and cost. However, no major breakthrough has been made in the upstream library preparation methods until the transposase-based Nextera method was invented. Nextera combines DNA fragmentation and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Kia, Amirali, Gloeckner, Christian, Osothprarop, Trina, Gormley, Niall, Bomati, Erin, Stephenson, Michelle, Goryshin, Igor, He, Molly Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240201/
https://ncbi.nlm.nih.gov/pubmed/28095828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0326-1
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