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T Oligo-Primed Polymerase Chain Reaction (TOP-PCR): A Robust Method for the Amplification of Minute DNA Fragments in Body Fluids

Body fluid DNA sequencing is a powerful noninvasive approach for the diagnosis of genetic defects, infectious agents and diseases. The success relies on the quantity and quality of the DNA samples. However, numerous clinical samples are either at low quantity or of poor quality due to various reason...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nai, Yu-Shin, Chen, Tzu-Han, Huang, Yu-Feng, Midha, Mohit K., Shiau, Hsin-Chieh, Shen, Chen-Yang, Chen, Chien-Jen, Yu, Alice L., Chiu, Kuo Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240146/
https://ncbi.nlm.nih.gov/pubmed/28094343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40767
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