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Thiol-Based Redox Modulation of Soluble Guanylyl Cyclase, the Nitric Oxide Receptor

Significance: Soluble guanylyl cyclase (sGC), which produces the second messenger cyclic guanosine 3′, 5′-monophosphate (cGMP), is at the crossroads of nitric oxide (NO) signaling: sGC catalytic activity is both stimulated by NO binding to the heme and inhibited by NO modification of its cysteine (C...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Autor principal: Beuve, Annie
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240013/
https://ncbi.nlm.nih.gov/pubmed/26906466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6591
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