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Accumulation of glycerophosphocholine (GPC) by renal cells: osmotic regulation of GPC:choline phosphodiesterase.

Although GPC has long been recognized as a degradation product of phosphatidylcholine, only recently is there wide appreciation of its role as a compatible and counteracting osmolyte that protects cells from osmotic stress. GPC is osmotically regulated in renal cells. Its level varies directly with...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Zablocki, K, Miller, S P, Garcia-Perez, A, Burg, M B
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7820
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