Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas

Pituitary adenomas constitute 15-20% of intracranial neoplasms. Previously we reported that cyclin-dependent kinase 5 (CDK5) is upregulated in pituitary tumors associated with activating protein p35, and plays an essential role in pituitary adenomas progression. Here we explored the mechanisms of CD...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Xie, Weiyan, Liu, Chunhui, Wu, Dan, Li, Zhenye, Li, Chuzhong, Zhang, Yazhuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
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Research Paper: Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239444/
https://ncbi.nlm.nih.gov/pubmed/27438154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10550
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