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A Phase 1 dose escalation study of NEO-102 in patients with refractory colon and pancreatic cancer
PURPOSE: NEO-102 is a novel chimeric IgG1 monoclonal antibody which recognizes a variant form of MUC5AC expressed specifically by human pancreatic and colorectal tumors. Preclinical models have demonstrated encouraging signs of antitumor activity through antibody-dependent cell-mediated cytotoxicity...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancer Chemother Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238716/ https://ncbi.nlm.nih.gov/pubmed/27449137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3108-5 |
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