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Disruption of Proline Synthesis in Melanoma Inhibits Protein Production Mediated by the GCN2 Pathway

Many processes are deregulated in melanoma cells and one of those is protein production. While much is known about protein synthesis in cancer cells, effective ways of therapeutically targeting this process remains an understudied area of research. A process that is upregulated in melanoma compared...

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Publicat a:Mol Cancer Res
Autors principals: Kardos, Gregory R., Wastyk, Hannah C., Robertson, Gavin P.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238710/
https://ncbi.nlm.nih.gov/pubmed/26082174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0048
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