Suppression of β1-Integrin in Gonadotropin-Releasing Hormone Cells Disrupts Migration and Axonal Extension Resulting in Severe Reproductive Alterations

Reproduction in mammals is dependent on the function of hypothalamic neurons whose axons project to the hypothalamic median eminence (ME) where they release gonadotropin-releasing hormone (GnRH) into a specialized capillary network for delivery to the anterior pituitary. These neurons originate pren...

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Vydáno v:J Neurosci
Hlavní autoři: Parkash, Jyoti, Cimino, Irene, Ferraris, Nicoletta, Casoni, Filippo, Wray, Susan, Cappy, Hélène, Prevot, Vincent, Giacobini, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238668/
https://ncbi.nlm.nih.gov/pubmed/23175850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3057-12.2012
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