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Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized dihydropyrimidone–α-acyloxycarboxamide compounds were ob...

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Veröffentlicht in:Beilstein J Org Chem
Hauptverfasser: Boukis, Andreas C, Monney, Baptiste, Meier, Michael A R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238564/
https://ncbi.nlm.nih.gov/pubmed/28179948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.7
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