Low autocrine interferon beta production as a gene therapy approach for AIDS: Infusion of interferon beta-engineered lymphocytes in macaques chronically infected with SIVmac251

BACKGROUND: The aim of this study was to evaluate gene therapy for AIDS based on the transduction of circulating lymphocytes with a retroviral vector giving low levels of constitutive macaque interferon β production in macaques chronically infected with a pathogenic isolate of SIVmac251. RESULTS: Tw...

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Detalhes bibliográficos
Main Authors: Gay, Wilfried, Lauret, Evelyne, Boson, Bertrand, Larghero, Jérome, Matheux, Franck, Peyramaure, Sophie, Rousseau, Véronique, Dormont, Dominique, De Maeyer, Edward, Le Grand, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523856/
https://ncbi.nlm.nih.gov/pubmed/15447786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-29
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