Nucleophilic displacement reactions of 5′-derivatised nucleosides in a vibration ball mill

Vibration ball-milling in a zirconia-lined vessel afforded clean and quantitative nucleophilic displacement reactions between 4-methoxybenzylthiolate salts and nucleoside 5′-halides or 5′-tosylates in five to 60 minutes. Under these conditions, commonly-encountered nucleoside cyclisation byproducts...

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Bibliografiska uppgifter
I publikationen:Beilstein J Org Chem
Huvudupphovsmän: Eguaogie, Olga, Conlon, Patrick F, Ravalico, Francesco, Sweet, Jamie S T, Elder, Thomas B, Conway, Louis P, Lennon, Marc E, Hodgson, David R W, Vyle, Joseph S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Beilstein-Institut 2017
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Full Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238552/
https://ncbi.nlm.nih.gov/pubmed/28179952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.11
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