High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy

Evidence indicates that hyaluronic acid (HA) mitigates tendinopathy, but the effect of molecular weight is unclear. We investigated the effects of different concentrations and different molecular weights of HA (350 kDa, 1500 kDa, and 3000 kDa) on matrix metalloproteinase (MMP)-1 and -3 expression in...

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Udgivet i:Sci Rep
Main Authors: Wu, Po-Ting, Kuo, Li-Chieh, Su, Fong-Chin, Chen, Shih-Yao, Hsu, Tai-I, Li, Chung-Yi, Tsai, Kuen-Jer, Jou, I-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238506/
https://ncbi.nlm.nih.gov/pubmed/28091588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40840
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