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High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy

Evidence indicates that hyaluronic acid (HA) mitigates tendinopathy, but the effect of molecular weight is unclear. We investigated the effects of different concentrations and different molecular weights of HA (350 kDa, 1500 kDa, and 3000 kDa) on matrix metalloproteinase (MMP)-1 and -3 expression in...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wu, Po-Ting, Kuo, Li-Chieh, Su, Fong-Chin, Chen, Shih-Yao, Hsu, Tai-I, Li, Chung-Yi, Tsai, Kuen-Jer, Jou, I-Ming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238506/
https://ncbi.nlm.nih.gov/pubmed/28091588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40840
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