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High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy

Evidence indicates that hyaluronic acid (HA) mitigates tendinopathy, but the effect of molecular weight is unclear. We investigated the effects of different concentrations and different molecular weights of HA (350 kDa, 1500 kDa, and 3000 kDa) on matrix metalloproteinase (MMP)-1 and -3 expression in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Po-Ting, Kuo, Li-Chieh, Su, Fong-Chin, Chen, Shih-Yao, Hsu, Tai-I, Li, Chung-Yi, Tsai, Kuen-Jer, Jou, I-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238506/
https://ncbi.nlm.nih.gov/pubmed/28091588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40840
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