Antisense oligodeoxynucleotide to the cystic fibrosis gene inhibits anion transport in normal cultured sweat duct cells.

We have tested the hypothesis that the cystic fibrosis (CF) gene product, called the CF transmembrane conductance regulator (CFTR), mediates anion transport in normal human sweat duct cells. Sweat duct cells in primary culture were treated with oligodeoxynucleotides that were antisense to the CFTR g...

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Bibliographic Details
Main Authors: Sorscher, E J, Kirk, K L, Weaver, M L, Jilling, T, Blalock, J E, LeBoeuf, R D
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52382/
https://ncbi.nlm.nih.gov/pubmed/1715578
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