MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

As one of the major risks for urolithiasis, hyperoxaluria can be caused by genetic defect or dietary intake. And high oxalate induced renal epithelial cells injury is related to oxidative stress and mitochondrial dysfunction. Here, we investigated whether MitoTEMPO, a mitochondria-targeted antioxida...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Zhang, Jiaqiao, Wang, Qing, Xu, Chuou, Lu, Yuchao, Hu, Henglong, Qin, Baolong, Wang, Yufeng, He, Deng, Li, Cong, Yu, Xiao, Wang, Shaogang, Liu, Jihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237742/
https://ncbi.nlm.nih.gov/pubmed/28116040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7528090
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