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C0818, a novel curcumin derivative, interacts with Hsp90 and inhibits Hsp90 ATPase activity

The aims of the present study were to estimate the affinity between 3,5-(E)-bis(3-methoxy-4-hydroxybenzal)-4-piperidinone hydrochloride (C0818) and heat shock protein 90 (Hsp90) and to investigate the inhibitory effects of this compound on Hsp90 ATPase activity. Fluorescence spectroscopy was used to...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Fan, Yingjuan, Liu, Yang, Zhang, Lianru, Cai, Fang, Zhu, Liping, Xu, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237709/
https://ncbi.nlm.nih.gov/pubmed/28119813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.05.014
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