GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity

GM-CSF and IL-3 are hematopoietic cytokines that also modulate the effector functions of several immune cell subsets. In particular, GM-CSF and IL-3 exert a significant control on monocyte and macrophage effector functions, as assessed in experimental models of inflammatory and autoimmune diseases a...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Borriello, Francesco, Iannone, Raffaella, Di Somma, Sarah, Loffredo, Stefania, Scamardella, Eloise, Galdiero, Maria Rosaria, Varricchi, Gilda, Granata, Francescopaolo, Portella, Giuseppe, Marone, Gianni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237654/
https://ncbi.nlm.nih.gov/pubmed/28138327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00680
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