Anti-allodynic effect of Buja in a rat model of oxaliplatin-induced peripheral neuropathy via spinal astrocytes and pro-inflammatory cytokines suppression

BACKGROUND: Oxaliplatin, a widely used anticancer drug against metastatic colorectal cancer, can induce acute peripheral neuropathy, which is characterized by cold and mechanical allodynia. Activation of glial cells (e.g. astrocytes and microglia) and increase of pro-inflammatory cytokines (e.g. IL-...

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Опубликовано в: :BMC Complement Altern Med
Главные авторы: Jung, Yongjae, Lee, Ji Hwan, Kim, Woojin, Yoon, Sang Hyub, Kim, Sun Kwang
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237549/
https://ncbi.nlm.nih.gov/pubmed/28088201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1556-z
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