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Two silencing sub-domains of v-erbA synergize with each other, but not with RXR.
The thyroid hormone receptor (TR) and the retinoic acid receptor (RAR) induce gene expression in the presence of specific ligand and repress transcription in the absence of hormone. This repression is mediated by an active silencing mechanism rather then by interference with DNA binding activators....
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1994
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523754/ https://ncbi.nlm.nih.gov/pubmed/7800478 |
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