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A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress.

The HAP1 protein (also known as APE/Ref-1) is a bifunctional human nuclear enzyme required for repair of apurinic/apyrimidinic sites in DNA and reactivation of oxidized proto-oncogene products. To gain insight into the biological roles of HAP1, the effect of expressing antisense HAP1 RNA in HeLa cel...

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Bibliografiske detaljer
Main Authors: Walker, L J, Craig, R B, Harris, A L, Hickson, I D
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523752/
https://ncbi.nlm.nih.gov/pubmed/7800476
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